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Medication Safety, Interactions & Toxicity – Quiz 3

Question 1 of 30

A nurse should avoid administering warfarin with which medication?

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Medication Safety, Interactions & Toxicity – Quiz 3 Practice Questions

Review these Medication Safety, Interactions & Toxicity – Quiz 3 nursing practice questions with answer choices and explanations.

Question 1

A nurse should avoid administering warfarin with which medication?

  1. Aspirin
  2. Acetaminophen
  3. Insulin
  4. Metformin
View answer and explanation

Correct answer:

  1. Aspirin

Explanation: Aspirin increases bleeding risk when combined with warfarin.

Question 2

Which laboratory value should be monitored for a client taking vancomycin?

  1. WBC
  2. Peak and trough levels
  3. Glucose
  4. Platelets
View answer and explanation

Correct answer:

  1. Peak and trough levels

Explanation: Vancomycin requires peak and trough monitoring to prevent toxicity.

Question 3

A nurse should monitor for which adverse effect of vancomycin?

  1. Hearing loss
  2. Hypertension
  3. Constipation
  4. Hypoglycemia
View answer and explanation

Correct answer:

  1. Hearing loss

Explanation: Vancomycin can cause ototoxicity.

Question 4

Which medication is considered high-alert due to risk of hypoglycemia?

  1. Insulin
  2. Ibuprofen
  3. Omeprazole
  4. Aspirin
View answer and explanation

Correct answer:

  1. Insulin

Explanation: Insulin is a high-alert medication.

Question 5

A client taking digoxin should have which lab monitored?

  1. Calcium
  2. Potassium
  3. Sodium
  4. Chloride
View answer and explanation

Correct answer:

  1. Potassium

Explanation: Low potassium increases risk of digoxin toxicity.

Question 6

Which medication should not be crushed?

  1. Extended-release tablets
  2. Chewable tablets
  3. Capsules
  4. Liquid medications
View answer and explanation

Correct answer:

  1. Extended-release tablets

Explanation: Crushing extended-release alters drug release.

Question 7

Which medication is contraindicated with nitrates?

  1. Sildenafil
  2. Metformin
  3. Aspirin
  4. Insulin
View answer and explanation

Correct answer:

  1. Sildenafil

Explanation: Combination causes severe hypotension.

Question 8

A nurse should monitor for which adverse effect of aminoglycosides?

  1. Ototoxicity
  2. Hypoglycemia
  3. Constipation
  4. Hypertension
View answer and explanation

Correct answer:

  1. Ototoxicity

Explanation: Aminoglycosides damage hearing.

Question 9

Which medication is used to reverse warfarin toxicity?

  1. Protamine sulfate
  2. Vitamin K
  3. Naloxone
  4. Flumazenil
View answer and explanation

Correct answer:

  1. Vitamin K

Explanation: Vitamin K reverses warfarin.

Question 10

A nurse should monitor which organ function for clients taking NSAIDs long-term?

  1. Kidneys
  2. Lungs
  3. Brain
  4. Skin
View answer and explanation

Correct answer:

  1. Kidneys

Explanation: NSAIDs can cause renal damage.

Question 11

Which medication is most likely to cause photosensitivity?

  1. Tetracycline
  2. Penicillin
  3. Metformin
  4. Warfarin
View answer and explanation

Correct answer:

  1. Tetracycline

Explanation: Tetracycline increases sensitivity to sunlight.

Question 12

A nurse should instruct a client taking lithium to:

  1. Follow a low-sodium diet
  2. Maintain consistent sodium intake
  3. Avoid fluids
  4. Take only when needed
View answer and explanation

Correct answer:

  1. Maintain consistent sodium intake

Explanation: Sodium imbalance increases lithium toxicity.

Question 13

Which medication requires monitoring for agranulocytosis?

  1. Clozapine
  2. Metformin
  3. Ibuprofen
  4. Insulin
View answer and explanation

Correct answer:

  1. Clozapine

Explanation: Clozapine suppresses bone marrow.

Question 14

Which medication may cause serotonin syndrome?

  1. SSRIs
  2. Antibiotics
  3. Insulin
  4. Diuretics
View answer and explanation

Correct answer:

  1. SSRIs

Explanation: SSRIs increase serotonin levels.

Question 15

Which symptom indicates serotonin syndrome?

  1. Bradycardia
  2. Hyperthermia
  3. Constipation
  4. Dry skin
View answer and explanation

Correct answer:

  1. Hyperthermia

Explanation: Serotonin syndrome causes hyperthermia.

Question 16

Which medication should be avoided in children due to Reye's syndrome?

  1. Aspirin
  2. Ibuprofen
  3. Acetaminophen
  4. Amoxicillin
View answer and explanation

Correct answer:

  1. Aspirin

Explanation: Aspirin can cause Reye's syndrome.

Question 17

Which medication can cause tendon rupture?

  1. Fluoroquinolones
  2. Penicillin
  3. Aspirin
  4. Metformin
View answer and explanation

Correct answer:

  1. Fluoroquinolones

Explanation: Fluoroquinolones increase tendon rupture risk.

Question 18

Which medication should be taken with food to prevent gastric irritation?

  1. NSAIDs
  2. Levothyroxine
  3. Omeprazole
  4. Insulin
View answer and explanation

Correct answer:

  1. NSAIDs

Explanation: NSAIDs irritate the stomach.

Question 19

Which medication should be taken on an empty stomach?

  1. Levothyroxine
  2. Ibuprofen
  3. Aspirin
  4. Iron
View answer and explanation

Correct answer:

  1. Levothyroxine

Explanation: Levothyroxine absorbs best on empty stomach.

Question 20

A nurse should monitor for which adverse effect of beta blockers?

  1. Bradycardia
  2. Tachycardia
  3. Hyperglycemia
  4. Diarrhea
View answer and explanation

Correct answer:

  1. Bradycardia

Explanation: Beta blockers reduce heart rate.

Question 21

Which medication is used to treat anaphylaxis?

  1. Epinephrine
  2. Insulin
  3. Warfarin
  4. Aspirin
View answer and explanation

Correct answer:

  1. Epinephrine

Explanation: Epinephrine is first-line treatment.

Question 22

Which medication should be avoided in asthma?

  1. Beta blockers
  2. Insulin
  3. Antibiotics
  4. Diuretics
View answer and explanation

Correct answer:

  1. Beta blockers

Explanation: Beta blockers can cause bronchospasm.

Question 23

Which medication is used to treat Parkinson's disease?

  1. Levodopa
  2. Warfarin
  3. Insulin
  4. Metformin
View answer and explanation

Correct answer:

  1. Levodopa

Explanation: Levodopa increases dopamine.

Question 24

Which medication requires monitoring for pancreatitis?

  1. Exenatide
  2. Insulin
  3. Metformin
  4. Warfarin
View answer and explanation

Correct answer:

  1. Exenatide

Explanation: Exenatide can cause pancreatitis.

Question 25

Which medication causes orange discoloration of urine?

  1. Rifampin
  2. Warfarin
  3. Metformin
  4. Insulin
View answer and explanation

Correct answer:

  1. Rifampin

Explanation: Rifampin discolors body fluids.

Question 26

Which medication requires monitoring for bleeding gums?

  1. Warfarin
  2. Insulin
  3. Metformin
  4. Ibuprofen
View answer and explanation

Correct answer:

  1. Warfarin

Explanation: Warfarin increases bleeding risk.

Question 27

Which medication can cause hyperkalemia?

  1. Spironolactone
  2. Furosemide
  3. Hydrochlorothiazide
  4. Mannitol
View answer and explanation

Correct answer:

  1. Spironolactone

Explanation: Potassium-sparing diuretics increase potassium.

Question 28

Which medication requires monitoring for bone density loss?

  1. Glucocorticoids
  2. Antibiotics
  3. Insulin
  4. Diuretics
View answer and explanation

Correct answer:

  1. Glucocorticoids

Explanation: Steroids cause osteoporosis.

Question 29

Which medication requires INR monitoring?

  1. Warfarin
  2. Heparin
  3. Insulin
  4. Metformin
View answer and explanation

Correct answer:

  1. Warfarin

Explanation: INR monitors warfarin therapy.

Question 30

Which medication is used to treat hypoglycemia?

  1. Glucagon
  2. Insulin
  3. Metformin
  4. Warfarin
View answer and explanation

Correct answer:

  1. Glucagon

Explanation: Glucagon raises blood glucose.