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Medication Safety, Adverse Effects & Clinical Monitoring – Quiz 1

Question 1 of 30

Which instructions should a nurse include for a client using a transdermal nitroglycerin patch? (Select the best answer.)

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Medication Safety, Adverse Effects & Clinical Monitoring – Quiz 1 Practice Questions

Review these Medication Safety, Adverse Effects & Clinical Monitoring – Quiz 1 nursing practice questions with answer choices and explanations.

Question 1

Which instructions should a nurse include for a client using a transdermal nitroglycerin patch? (Select the best answer.)

  1. Apply patch to same site daily
  2. Apply patch to a hairless area
  3. Apply patch at onset of pain
  4. Keep patch on for 24 hours
View answer and explanation

Correct answer:

  1. Apply patch to a hairless area

Explanation: Nitroglycerin patches should be applied to hairless areas to ensure proper absorption.

Question 2

A nurse is preparing to administer amitriptyline 150 mg PO. Tablets available are 75 mg. How many tablets should the nurse administer?

  1. 1 tablet
  2. 2 tablets
  3. 3 tablets
  4. 4 tablets
View answer and explanation

Correct answer:

  1. 2 tablets

Explanation: 150 ÷ 75 = 2 tablets.

Question 3

A client taking atenolol should be monitored for which adverse effect?

  1. Bradycardia
  2. Anemia
  3. Hypokalemia
  4. Neutropenia
View answer and explanation

Correct answer:

  1. Bradycardia

Explanation: Beta blockers like atenolol can cause bradycardia.

Question 4

A client taking phenytoin states, 'I will stop the medication once my seizures stop.' What is the nurse’s response?

  1. That is correct
  2. You can stop after 1 week
  3. You should not stop abruptly
  4. Take only when needed
View answer and explanation

Correct answer:

  1. You should not stop abruptly

Explanation: Phenytoin should not be stopped abruptly due to risk of seizures.

Question 5

A client taking allopurinol should understand which instruction?

  1. Take on empty stomach
  2. Drink at least 3 L of water daily
  3. Expect fever
  4. Stop if rash develops
View answer and explanation

Correct answer:

  1. Drink at least 3 L of water daily

Explanation: Increased fluid intake prevents kidney stones.

Question 6

Which finding should be reported immediately for a client taking clindamycin?

  1. Nausea
  2. Watery diarrhea
  3. Headache
  4. Bloating
View answer and explanation

Correct answer:

  1. Watery diarrhea

Explanation: Watery diarrhea may indicate C. difficile infection.

Question 7

Which condition should be reported before giving propranolol?

  1. Migraine
  2. Glaucoma
  3. Heart failure
  4. Depression
View answer and explanation

Correct answer:

  1. Heart failure

Explanation: Beta blockers can worsen heart failure.

Question 8

Celecoxib is prescribed for which condition?

  1. Depression
  2. Seizures
  3. Osteoarthritis
  4. Infection
View answer and explanation

Correct answer:

  1. Osteoarthritis

Explanation: Celecoxib is an NSAID used for arthritis.

Question 9

Which instruction is correct for a client taking lisinopril?

  1. Eat potassium-rich foods
  2. Report persistent cough
  3. Monitor cholesterol
  4. Stop if dizziness occurs
View answer and explanation

Correct answer:

  1. Report persistent cough

Explanation: ACE inhibitors commonly cause dry cough.

Question 10

Methimazole effectiveness is indicated by:

  1. Weight loss
  2. Increased urine
  3. Elevated temperature
  4. Decreased heart rate
View answer and explanation

Correct answer:

  1. Decreased heart rate

Explanation: Hyperthyroidism causes tachycardia; treatment lowers heart rate.

Question 11

A client taking phenytoin should:

  1. Expect red urine
  2. Take with antacids
  3. Maintain good oral hygiene
  4. Stop when seizures stop
View answer and explanation

Correct answer:

  1. Maintain good oral hygiene

Explanation: Phenytoin causes gingival hyperplasia.

Question 12

Methotrexate teaching should include:

  1. Take daily
  2. Avoid fluids
  3. Drink plenty of water
  4. Take NSAIDs freely
View answer and explanation

Correct answer:

  1. Drink plenty of water

Explanation: Hydration reduces toxicity.

Question 13

Lithium toxicity is indicated by:

  1. Constipation
  2. Fine tremor
  3. Coarse tremor
  4. Weight gain
View answer and explanation

Correct answer:

  1. Coarse tremor

Explanation: Coarse tremors indicate toxicity.

Question 14

Beclomethasone adverse effect includes:

  1. Tremors
  2. Oral thrush
  3. Constipation
  4. Headache
View answer and explanation

Correct answer:

  1. Oral thrush

Explanation: Inhaled steroids can cause oral candidiasis.

Question 15

Elevated TSH indicates:

  1. Hyperthyroidism
  2. Hypothyroidism
  3. Normal thyroid
  4. Adrenal disorder
View answer and explanation

Correct answer:

  1. Hypothyroidism

Explanation: High TSH indicates low thyroid hormone.

Question 16

Fentanyl toxicity is treated with:

  1. Atropine
  2. Naloxone
  3. Flumazenil
  4. Protamine
View answer and explanation

Correct answer:

  1. Naloxone

Explanation: Naloxone reverses opioid effects.

Question 17

Acetaminophen overdose causes:

  1. Tinnitus
  2. Vomiting
  3. Bradycardia
  4. Constipation
View answer and explanation

Correct answer:

  1. Vomiting

Explanation: Early toxicity includes nausea and vomiting.

Question 18

Carbamazepine requires monitoring for:

  1. Hearing loss
  2. Bone marrow suppression
  3. Hair loss
  4. Bradycardia
View answer and explanation

Correct answer:

  1. Bone marrow suppression

Explanation: It can cause agranulocytosis.

Question 19

Clopidogrel therapy requires monitoring for:

  1. Headache
  2. Black stools
  3. Dry mouth
  4. Fatigue
View answer and explanation

Correct answer:

  1. Black stools

Explanation: Black stools indicate GI bleeding.

Question 20

Levothyroxine overdose causes:

  1. Bradycardia
  2. Weight gain
  3. Tachypnea
  4. Cold intolerance
View answer and explanation

Correct answer:

  1. Tachypnea

Explanation: Excess thyroid hormone increases metabolism.

Question 21

Heparin antidote is:

  1. Vitamin K
  2. Protamine sulfate
  3. Naloxone
  4. Atropine
View answer and explanation

Correct answer:

  1. Protamine sulfate

Explanation: Protamine reverses heparin.

Question 22

Olanzapine adverse effect:

  1. Weight loss
  2. Weight gain
  3. Insomnia
  4. Diarrhea
View answer and explanation

Correct answer:

  1. Weight gain

Explanation: Antipsychotics cause weight gain.

Question 23

Alprazolam teaching should include:

  1. No sedation
  2. Avoid alcohol
  3. No dependence risk
  4. Stop abruptly
View answer and explanation

Correct answer:

  1. Avoid alcohol

Explanation: Alcohol increases CNS depression.

Question 24

MAOI diet should avoid:

  1. Milk
  2. Apples
  3. Avocados
  4. Celery
View answer and explanation

Correct answer:

  1. Avocados

Explanation: Tyramine-rich foods can cause hypertensive crisis.

Question 25

Spironolactone requires monitoring:

  1. Sodium
  2. Potassium
  3. Glucose
  4. Calcium
View answer and explanation

Correct answer:

  1. Potassium

Explanation: It causes hyperkalemia.

Question 26

Rifampin causes:

  1. Blue urine
  2. Orange secretions
  3. Clear urine
  4. Green stool
View answer and explanation

Correct answer:

  1. Orange secretions

Explanation: Rifampin turns body fluids orange.

Question 27

Clozapine requires monitoring:

  1. Liver enzymes
  2. WBC count
  3. Glucose
  4. Potassium
View answer and explanation

Correct answer:

  1. WBC count

Explanation: Risk of agranulocytosis.

Question 28

Digoxin toxicity includes:

  1. Constipation
  2. Nausea
  3. Insomnia
  4. Headache
View answer and explanation

Correct answer:

  1. Nausea

Explanation: Nausea and vomiting are early signs.

Question 29

Warfarin therapy is monitored using:

  1. WBC
  2. PT/INR
  3. Platelets
  4. aPTT
View answer and explanation

Correct answer:

  1. PT/INR

Explanation: PT/INR measures warfarin effect.

Question 30

Simvastatin teaching includes:

  1. Drink grapefruit juice
  2. Report muscle pain
  3. Take with antacids
  4. Avoid exercise
View answer and explanation

Correct answer:

  1. Report muscle pain

Explanation: Muscle pain may indicate rhabdomyolysis.